THIS ITINERARY AT A GLANCE
The Great River Road is a scenic treasure in the Land of Lincoln, offering breathtaking views of the Mississippi River, charming small towns, and historic landmarks. Spanning Alton to Grafton and beyond, this route is perfect for a three-day getaway filled with outdoor adventures, local cuisine, and cultural enlightenment.
Now, let history buffs, nature lovers, and road trippers unite: this itinerary will help every sort of group make the most of their explorations around one of Illinois’ premier regions.
Enjoy These Attractions and More:
- Lewis & Clark State Historic Site
- National Great Rivers Museum
- Elsah
- Two Rivers National Wildlife Refuge
- Audubon Center at Riverlands
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Great River Road Day-To-Day Itinerary
Day 1 of Things To Do in Southwest Illinois
Begin your journey in Hartford, where you can step back in time at the Lewis & Clark State Historic Site. This attraction commemorates the 1804 expedition and allows visitors to learn about the challenges the explorers faced as they set off to chart the western territories of the United States. The museum offers a variety of exhibits that detail the history of the expedition, including the role of local Native American tribes, the wildlife they encountered, and the tools they used. After exploring the historic site, enhance your knowledge even further at the Lewis & Clark Confluence Tower, located nearby. The tower stands at 180 feet tall and offers sweeping views of the confluence of the Mississippi and Missouri Rivers. On a clear day, you can see for miles in every direction, making it a perfect spot for photos and quiet reflection.
Next, make your way to Alton, a charming city with a rich history tied to the Mississippi River. Once there, visit the National Great Rivers Museum, where you can hear about the river’s importance to the development of the region and the country. The museum is housed near the Melvin Price Locks & Dam, and you can take a guided tour to learn how the locks help manage river traffic and prevent flooding. More good news: a short walkaway is the Robert Wadlow Statue, dedicated to the world’s tallest man. Standing at 8 feet 11 inches and born in Alton, Wadlow remains an iconic figure in the town.
For dinner, head to the Alton’s Bluff City Grill. This local favorite is known for its delicious fried chicken and home-style cooking, offering a great introduction to the area’s hearty cuisine. Alternatively, Castelli’s at 255 provides a great mix of Italian-American dishes, perfect for a group looking to enjoy a family-style meal in a cozy atmosphere.
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Day 2 of Southwest Illinois Attractions
Start your second day with a visit to Elsah, a charming village tucked along the Mississippi River. This small town is known for its well-preserved 19th-century buildings and picturesque river views. It’s the perfect place for a leisurely stroll, and you can stop by the local shops or simply enjoy the scenery. If you’re interested in local craftsmanship, head to David Stine Furniture in Dow, where you can watch artisans create custom wood furniture. The showroom is filled with beautiful, handcrafted pieces, making it a great stop for those interested in craftsmanship and design.
Continue your journey to Grafton, a riverside town known for its wineries and outdoor beauty. At the Grafton Winery and Vineyards, you will enjoy a tour of the winery while learning about the wine-making process and sampling some of the region’s best options. The tasting room is a cozy environment with views of the vineyard and the river beyond, making it an ideal stop for wine enthusiasts. Afterward, trek over to Pere Marquette State Park, one of Illinois’ largest state parks, where you can enjoy hiking, picnicking, or simply taking in the breathtaking views of the Mississippi River from the park’s scenic overlooks. The park is home to a wide variety of wildlife, making it a great spot for nature lovers to explore.
For dinner, try Aerie’s Resort, a Grafton gem where you can dine on the patio with a stunning view of the river. The resort boasts a diverse menu with options ranging from seafood to steaks, making it a great place for a relaxing meal after a day of exploration. The atmosphere is laid-back, and the view is unbeatable.
Day 3 of Southwest Illinois Activities
The final day should begin with a relaxing Hakuna Matata Boat Cruise at Grafton Harbor. The 49-passenger boat offers open-air seating on the upper deck and enclosed seating on the mid-deck, perfect for a peaceful tour of the Mississippi River. Enjoy River Rambler cruises or themed Sunset and Wine cruises available in the spring, summer, and fall.
Next, head to the Two Rivers National Wildlife Refuge via Brussels Ferry. This wildlife haven sits at the confluence of the Illinois and Mississippi Rivers, attracting over 200,000 waterfowl during migration. Take a walk on the levee trail or simply enjoy birdwatching from scenic overlooks. The area is perfect for hiking, biking, fishing, and seasonal activities like canoeing.
Interested in nature-focused fun? Visit Tree House Wildlife Center in Dow to explore this wildlife rehabilitation center. Open daily from 10 a.m. to 4 p.m., this premier attraction offers a chance to learn about local animals and their rehabilitation efforts.
Finish your nature-filled day at the Audubon Center at Riverlands, a sanctuary along the Mississippi River Flyway. The center is an excellent spot for birdwatching, where you can observe over 60 percent of North America’s migratory bird species.
Fora scrumptious meal to conclude your Land of Lincoln travel experience, enjoy family-style dining at Wittmond Hotel in Brussels, where hearty, home-cooked dishes are always on the menu. Alternatively, some prefer to indulge in fried chicken and comfort food at Pere Marquette Lodge Restaurant in Grafton.
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